Overview of Current Drug Discovery Activities in Africa and Their Links to International Efforts to Combat Tropical Infectious Diseases / Barthélemy Nyasse -- The National Cancer Institute and Natural Product-Based Drug Discovery in Africa / John A. Beutler, Gordon M. Cragg and David J. Newman -- Tuberculosis Drug Discovery: Target Identification and Validation / Digby F. Warner and Valerie Mizrahi -- Targeting Conserved Pathways as a Strategy for Novel Drug Development: Disabling the Cellular Stress Response / Adrienne L. Edkins and Gregory L. Blatch -- Natural Product-Based Drug Discovery in Africa: The Need for Integration into Modern Drug Discovery Paradigms / Eric M. Guantai and Kelly Chibale -- Searching for Drugs That Target Multiple Receptors for Anthelmintics from African Natural Products / Timothy G. Geary and Eliane Ubalijoro -- Application of In Silico, In Vitro and In Vivo ADMET/PK Platforms in Drug Discovery / Collen Masimirembwa and Roslyn Thelingwani -- Marine Bioprospecting in Southern Africa / Michael T. Davies-Coleman and Suthananda N. Sunassee -- Natural Product-Based Drug Discovery Against Neglected Diseases with Special Reference to African Natural Resources / Sami A. Khalid -- Now I Heal with Pride -- The Application of Screens-to-Nature Technology to Indigenous Knowledge Systems Research in Botswana: Implications for Drug Discovery / Kerstin Andrae-Marobela, Aku N. Ntumy, Masego Mokobela, Mthandazo Dube and Angelina Sosome, et al. -- Innovative Approaches to Exploiting Traditional Medicines in Malaria / Philippe Rasoanaivo and Solofoniaina Razafimahefa -- Anticancer Drug Repositioning Against Tropical Diseases: The Example of Methotrexate in the Treatment of Malaria / Alexis Nzila and Kelly Chibale -- Tackling the Problem of Antimalarial Resistance / John Okombo, Leah Mwai and Alexis Nzila -- Random and Rational Approaches to HIV Drug Discovery in Africa / R. Hewer, F. H. Kriel and J. Coates -- Structure-Based Design of Domain-Selective Angiotensin-Converting Enzyme Inhibitors / Ross G. Douglas and Edward D. Sturrock -- Natural Products and Antimalarial Drugs: Will Africa Provide the Next Major Breakthrough? / Ivan Addae-Mensah and Dorcas Osei-Safo -- Nanomedicine in the Development of Drugs for Poverty-Related Diseases / Rose Hayeshi, Boitumelo Semete, Lonji Kalombo, Lebogang Katata and Yolandy Lemmer, [et al.].
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